Colloquium Marie Sklodowska-Curie

Esta serie de coloquios ve la luz impulsada por el interés común de varios Institutos del Consejo Superior de Investigaciones Científicas (CSIC) que quieren traer a la sociedad los últimos avances científicos y la visión del mundo que surge de ellos.

El objetivo final es transmitir el mensaje de que la ciencia es un bien público que debe hacerse accesible a todos los ciudadanos. Una manera efectiva de enviar este mensaje es a través de la difusión de conocimiento que combina el rigor con la accesibilidad. Con este espíritu, esta serie quiere reunir a personalidades de renombre internacional de una variedad de campos de investigación y del mundo de la cultura, para compartir su experiencia con un amplio público.

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Contacto y sugerencias: coloquioscurie_at_gmail.com.

Próximo coloquio

New eyes to the nano-world of living cells

María García-Parajo Instituto de Ciencias Fotónicas
Salón de actos
Edificio central CSIC
Serrano 117

One general property and strategy of natural systems, including humans, is to organize different components by means of compartmentalization. This compartmentalization efficiently facilitates and orchestrates biological events in space and time. Cells are primary examples of well-defined biological compartments within tissues. However, cells also exhibit a number of compartmentalization strategies, including membrane-delimited intracellular organelles and multi-enzyme complexes. The compartmentalization of specific cellular functions, through spatial localization, increases regulation efficiency. At the nanometre scale, cells also organize their molecular components in a highly regulated way. Yet, visualization of these processes have been hidden until recently, due to the lack of non-invasive techniques that provide sufficient spatiotemporal resolution. A major breakthrough in optical microscopy occurred about 10 years ago when researchers invented different ways to overcome the barrier of diffraction of the light. The advent of these so-called super-resolution techniques and single molecule dynamic approaches are indeed providing new eyes to visualize the nano-world of living cells. From these studies, it is becoming clear that compartmentalization in space and time is a general feature of living cells and it operates from the cell membrane down to chromatin in the nucleus. In this talk, I will first describe the working principles of these advanced optical techniques and will then focus on recent studies in my group linking spatial and temporal organization at the nano- and meso-scales to different biological functions.

[Poster]

[Emisión en directo]